Divestment of rights to Alvesco, Omnaris and Zetonna to Covis Pharma
AstraZeneca has entered into an agreement with Covis Pharma B.V. (Covis Pharma) to sell its rights to the medicines Alvesco (ciclesonide), usedfor the treatment of persistent asthma, and Omnaris and Zetonna (ciclesonide), used for the treatment of nasal symptoms associated with rhinitis.
The rights cover markets outside the US and the US royalties for the medicines. Covis Pharma currently commercialises Alvesco, Omnaris and Zetonna in the US and will become the owner of the medicines upon closing.
The transaction does not include the transfer of any AstraZeneca employees or facilities.
Mark Mallon, Executive Vice President, Global Product and Portfolio Strategy, said: “One of our strategic objectives is to divest parts of our portfolio, allowing us to allocate resources to develop innovative new medicines to address unmet patient needs. Covis Pharma has strong capabilities in marketing medicines around the world, and our agreement with them means patients will continue to benefit from Alvesco, Omnaris and Zetonna.”
Michael Porter, Chief Executive Officer, Covis Pharma, said: “This is an exciting milestone for Covis Pharma and aligned with our strategy to build a global respiratory/allergy franchise.
When we acquired the US rights for Alvesco, Omnaris and Zetonna in 2017, we recognised the importance of these medicines in the respiratory and allergy therapeutic area and we look forward to extending our reach to meet the needs of patients and physicians around the world.”
Alvesco is an inhaled anti-inflammatory maintenance therapy delivered by a metered-dose inhaler to help control persistent asthma.
Omnaris and Zetonna are nasal sprays for the treatment of nasal symptoms associated with seasonal allergic and allergic/non-allergic perennial rhinitis.
The active ingredient in all three medicines is ciclesonide, a synthetic corticosteroid that helps relieve inflammation.
Covis Pharma will pay AstraZeneca $350 million upon closing, in addition to conditional sales-related payments of up to $21 million over four years from 2019. The agreement is subject to customary closing conditions and is expected to complete by the end of 2018.
As AstraZeneca will not maintain a significant ongoing interest in the medicines following completion, the payments will be recognised as Other Operating Income in the Company’s financial statements. Combined 2017 Product Sales of Alvesco, Omnaris and Zetonna,recorded by AstraZeneca, were $106 million.
The agreement does not affect the Company’s financial guidance for 2018.
About Covis Pharma
Covis Pharma is headquartered in Zug, Switzerland and is a global speciality pharmaceutical company that markets therapeutic solutions for patients with life-threatening conditions and chronic illnesses. Additional information is available at www.covispharma.com.
AstraZeneca is a global, science-led biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines, primarily for the treatment of diseases in three therapy areas – Oncology, Cardiovascular, Renal & Metabolism and Respiratory. AstraZeneca operates in over 100 countries and its innovative medicines are used by millions of patients worldwide. For more information, please visit www.astrazeneca.com and follow us on @AstraZeneca.
Drugs & Medications
Drugs & Medications
- Side Effects
- Side Effects
Ciclesonide is used to relieve seasonal and year-round allergy symptoms of the nose such as stuffy/runny nose, itching, and sneezing. This medication belongs to a class of drugs known as corticosteroids. It works by reducing swelling (inflammation) in the nasal passages.
Read the Patient Information Leaflet provided by your pharmacist before you start using ciclesonide nasal spray and each time you get a refill. Follow the instructions on how to properly use this medication. If you have any questions, ask your doctor or pharmacist.
Gently blow your nose before using this drug. Follow the instructions on how to properly prime the canister if you are using it for the first time, if you have not used it for 10 days or more, or if the canister and actuator become separated.
Use this medication in the nose as directed by your doctor, usually once a day in both nostrils. Do not use more than 1 spray in each nostril daily as this may increase the risk of side effects. Do not spray this medication in your eyes or directly onto the nasal septum (the wall between your nostrils).
Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time each day.
Clean the outside of the nose piece regularly with a clean dry tissue. Keep track of the number of sprays used from the container with the dose indicator. Discard the container after the dose indicator reads zero.
You may feel the drug start to work within 2 days, but it may take 1 to 2 weeks before the full benefit of this drug takes effect. Tell your doctor if your condition does not improve or if it worsens.
Nasal dryness/irritation or mild nosebleeds may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including: severe nosebleeds, pain in your nose, a whistling sound when you breathe, eye pain, signs of infection (such as white patches in your nose/back of your throat, persistent sore throat, fever, chills).
Rarely, it is possible that corticosteroids given in the nose will be absorbed into the bloodstream. This can lead to side effects of too much corticosteroid.
These side effects are more ly in children and people who use this medication for a long time and in high doses.
Tell your doctor right away if any of the following side effects occur: unusual/extreme tiredness, weight loss, headache, swelling ankles/feet, increased thirst/urination, vision problems.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US –
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
Zetonna Coupons and Discounts
Zetonna is a nasal spray that is used to relieve allergy symptoms an itchy and stuffy nose. It contains a corticosteroid called ciclesonide.
Zetonna costs around $230 to $260 for one canister of spray, and can be difficult to afford without insurance coverage or a Zetonna copay card.
To help lower the price of this expensive allergy medication, take advantage of our Zetonna coupons or discount card to save as much as 75% off the retail price of Zetonna at pharmacies near you. Learn more about our coupons and discounts below.
Internet Drug Coupons keeps track of coupons, copay cards, rebates and more from drug manufacturers and passes the savings information on to our visitors whenever a deal is available.
Unfortunately, there are no Zetonna manufacturer coupons available at this time, but check back with us often to see if any offers become available.
In the meantime, use our Zetonna internet drug coupon or our discount card to save on your prescription.
2. Zetonna Internet Drug Coupon
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Our Zetonna drug coupon is always available on our site, and it’s good for 20-75% off the retail price of Zetonna in most pharmacies nationwide.
To use one of our coupons, just select how you would to receive it: by SMS, email, or printer. You will get your coupon instantly–no registration required.
Once you have your Zetonna coupon, present it to your pharmacist along with your prescription. He or she will add your discount at the counter.
Other coupons related to: Antihistamine – Hay Fever
Get Our Prescription Discount Card
If you regularly fill prescriptions, you will benefit from our free Rx discount card that works for Zetonna and thousands of other medications. To request one, just click the link and fill out your mailing address.
You will receive a plastic discount card in the mail within two weeks. Carry it with you in your wallet for convenient savings whenever you need to fill a prescription. This card is accepted at all major U.S.
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Read information about Zetonna below to learn about its common uses. If you have questions about this medicine, please consult with your doctor or pharmacist and be sure to inform them of all the medications you are currently taking.
Zetonna is used to treat seasonal or year-round allergic rhinitis when symptoms manifest in the nasal passages. Zetonna contains a corticosteroid that reduces itching and inflammation, which helps to relieve nasal allergy symptoms.
Zetonna Side Effects:
Zetonna can cause side effects. Some common side effects from using Zetonna nasal spray include dry nasal passages, headache, and nose bleeds. Report any severe or frequent nosebleeds or headaches to your doctor as soon as possible.
When used for extended periods of time Zetonna may weaken the body’s immune system. Call your doctor if you have a fever or frequently get infections.
Other serious side effects that should be reported right away include: unusual and persistent fatigue, nausea and vomiting, crusting in the nose, or hearing a whistling sound when you breathe.
Zetonna Generics & Similar Drugs:
The generic name for Zetonna is ciclesonide, but there is currently no generic version available on the market. Similar drugs include Nasacort AQ (triamcinolone) and Flonase (fluticasone propionate). Browse our site for coupons and other deals for any of these similar medications. If you find a cheaper option, ask your doctor about switching.